During fasting, insulin levels drop, allowing stored fat to be mobilized for energy. After ~12 hours, glycogen stores deplete, and the body starts burning fat for fuel. By 24 hours, ketosis begins, increasing fat oxidation and metabolic flexibility.
After ~24-30 hours, the body activates autophagy, a process where damaged cells and proteins are recycled. Autophagy is linked to reduced inflammation, improved brain function, and longevity. Studies suggest fasting-induced autophagy may lower the risk of neurodegenerative diseases like Alzheimer’s.
Human Growth Hormone (HGH) increases by up to 500% after 24 hours, promoting muscle preservation and fat loss. Insulin Sensitivity improves, helping regulate blood sugar and reduce the risk of Type 2 diabetes. AMPK Activation, a longevity enzyme, enhances mitochondrial function and cellular health.
